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Anti-Akt (pan) antibody

Anti-Akt (pan) antibody

ArtNr	STJ99074-200
Hersteller	St John's Laboratory
Menge	200ul
Kategorie	Oncology Neuroscience Aging & Neurological Disorders Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Immunoprecipitation Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	WB, IP
Clon	3B11-G8-B1
Specific against	Human, Mouse, Rat
Host	Mouse
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	RAC-alpha serine/threonine-protein kinase </br> Protein kinase B </br> PKB </br> Protein kinase B alpha </br> PKB alpha </br> Proto-oncogene c-Akt </br> RAC-PK-alpha
Similar products	RAC-alpha serine/threonine-protein kinase Protein kinase B PKB Protein kinase B alpha PKB alpha Proto-oncogene c-Akt RAC-PK-alpha
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Clonality	Monoclonal
Conjugation	Unconjugated
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Uniprot ID	P31749
Storage	Store at-20° C, and avoid repeat freeze-thaw cycles.
Concentration	1 mg/ml
Description	Mouse monoclonal to Akt (pan).
Gene ID	207
Gene symbol	AKT1
Immunogen	Purified recombinant human AKT1 protein fragments expressed in E.coli.
Short Description	Mouse monoclonal against Akt (pan)
Tissue specificity	Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages.
Cellular localization	Cytoplasm. Nucleus. Cell membrane. Nucleus after activation by integrin-linked protein kinase 1 (ILK1). Nuclear translocation is enhanced by interaction with TCL1A. Phosphorylation on Tyr-176 by TNK2 results in its localization to the cell membrane where it is targeted for further phosphorylations on Thr-308 and Ser-473 leading to its activation and the activated form translocates to the nucleus. Colocalizes with WDFY2 in intracellular vesicles.
Molecular weight	60kDa
Dilution range	WB 1:1000
Alternative names	RAC-alpha serine/threonine-protein kinase Protein kinase B PKB Protein kinase B alpha PKB alpha Proto-oncogene c-Akt RAC-PK-alpha
Protein name	RAC-alpha serine/threonine-protein kinase Protein kinase B PKB Protein kinase B alpha PKB alpha Proto-oncogene c-Akt RAC-PK-alpha
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	P31749_HUMAN

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Menge: 200ul

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