Anti-p300 antibody

Unconjugated

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Store at-20° C, and avoid repeat freeze-thaw cycles.

p300 is a protein encoded by the EP300 gene which is approximately 264, 1 kDa. p300 is localised to the cytoplasm and nucleus. It is involved in signalling by NOTCH1, transcription-coupled nucleotide excision repair and the regulation of lipid metabolism. It functions as a histone acetyl-transferase that regulates transcription via chromatin remodelling and is important in the processes of cell proliferation and differentiation. p300 is expressed in the liver, nervous system, blood skin and muscle. Mutations in the EP300 gene may result in colorectal cancer. STJ97645 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of p300 protein.

EP300

Internal

Cytoplasm
Nucleus
Chromosome
Localizes To Active Chromatin: Colocalizes With Histone H3 Acetylated And/Or Crotonylated At 'Lys-18' (H3k18ac And H3k18cr
Respectively)
In The Presence Of Alx1 Relocalizes From The Cytoplasm To The Nucleus
Colocalizes With Rock2 In The Nucleus

Anti-Histone Acetyltransferase P300 antibody
Anti-P300 Hat antibody
Anti-E1a-Associated Protein P300 antibody
Anti-Histone Butyryltransferase P300 antibody
Anti-Histone Crotonyltransferase P300 antibody
Anti-Protein 2-Hydroxyisobutyryltransferase P300 antibody
Anti-Protein Propionyltransferase P300 antibody
Anti-EP300 P300 antibody

FOR RESEARCH USE ONLY (RUO).