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Anti-Phospho-GSK Beta (S9) antibody Europäischer Partner

ArtNr STJ90284-100
Hersteller St John's Laboratory
Menge 100ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IF, IP, ELISA, IHC-P
Specific against Human, Mouse, Rat
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Anti-Glycogen Synthase Kinase-3 Beta antibody</br>Anti-Gsk-3 Beta antibody</br>Anti-Serine/Threonine-Protein Kinase Gsk3b antibody</br>Anti-GSK3B antibody
Similar products Anti-Glycogen Synthase Kinase-3 Beta antibody
Anti-Gsk-3 Beta antibody
Anti-Serine/Threonine-Protein Kinase Gsk3b antibody
Anti-GSK3B antibody
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Uniprot ID
P49841
Storage
Store at-20° C, and avoid repeat freeze-thaw cycles.
Concentration
1 mg/ml
Description
GSK3beta is a protein encoded by the GSK3B gene which is approximately 46, 7 kDa. GSK3beta is localised to the cytoplasm, nucleus and cell membrane. it is involved in the common cytokine receptor gamma-chain family signalling pathways, RET signalling, GAB1 signalosome, regulation of lipid metabolism and insulin signalling-generic cascades. It is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily and is involved in energy metabolism, neuronal cell development, and body pattern formation. GSK3beta is expressed in the testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney. Mutations in the GSK3B gene may result in Alzheimer disease and muscle hypertrophy. STJ90284 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous GSK3beta protein which only binds about S9 when S9 is phosphorylated.
Gene ID
Gene symbol
Immunogen
Synthesized peptide derived from human GSK3beta around the phosphorylation site of S9.
Immunogen region
1-80 aa
Short Description
Rabbit polyclonal against Phospho-GSK beta (S9)
Tissue specificity
Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney. Colocalizes with EIF2AK2/PKR and TAU in the Alzheimer disease (AD) brain.
Cellular localization
Cytoplasm
Nucleus
Cell Membrane
The Phosphorylated Form Shows Localization To Cytoplasm And Cell Membrane
The Memo1-Rhoa-Diaph1 Signaling Pathway Controls Localization Of The Phosphorylated Form To The Cell Membrane
Molecular weight
47 kDa
Dilution range
IF 1:50-200
WB 1:500-1:2000
IHC 1:100-1:300
IP 2-5 ug/mg lysate
ELISA 1:5000
Alternative names
Anti-Glycogen Synthase Kinase-3 Beta antibody
Anti-Gsk-3 Beta antibody
Anti-Serine/Threonine-Protein Kinase Gsk3b antibody
Anti-GSK3B antibody
Protein name
Glycogen Synthase Kinase-3 Beta
Gsk-3 Beta
Serine/Threonine-Protein Kinase Gsk3b
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
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