Anti-DFFA antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

O00273

Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

DFFA

Rabbit polyclonal against DFFA

Calculated: 29kDa/36kDa. Observed: 35kDa, 45kDa

Anti-Dna Fragmentation Factor Subunit Alpha antibody
Anti-Dna Fragmentation Factor 45 Kda Subunit antibody
Anti-Dff-45 antibody
Anti-Inhibitor Of Cad antibody
Anti-Icad antibody
Anti-DFFA DFF1 DFF45 H13 antibody

FOR RESEARCH USE ONLY (RUO).