ArtNr |
STJ29127-50 |
Hersteller |
St John's Laboratory
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IF, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Tnf Receptor-Associated Factor 4 antibody</br>Anti-Cysteine-Rich Domain Associated With Ring And Traf Domains Protein 1 antibody</br>Anti-Metastatic Lymph Node Gene 62 Protein antibody</br>Anti-Mln 62 antibody</br>Anti-Ring Finger Protein 83 antibody |
Similar products |
Anti-Tnf Receptor-Associated Factor 4 antibodyAnti-Cysteine-Rich Domain Associated With Ring And Traf Domains Protein 1 antibodyAnti-Metastatic Lymph Node Gene 62 Protein antibodyAnti-Mln 62 antibodyAnti-Ring Finger Protein 83 antibody |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q9BUZ4 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 251-470 of human TRAF4 (NP_004286. 2). |
Short Description |
Rabbit polyclonal against TRAF4 |
Tissue specificity |
Expressed in epithelial cells of thymus, dendritic cells of lymph node, and in the basal cell layer of epithelia such as epidermis, nasopharynx, respiratory tract, salivary gland, and esophagus. |
Cellular localization |
CytoplasmNucleusPerinuclear RegionCell JunctionTight JunctionCell MembranePeripheral Membrane ProteinCytoplasmic SideCytoskeleton |
Molecular weight |
Calculated: 22kDa/53kDa. Observed: 54kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 |
Alternative names |
Anti-Tnf Receptor-Associated Factor 4 antibodyAnti-Cysteine-Rich Domain Associated With Ring And Traf Domains Protein 1 antibodyAnti-Metastatic Lymph Node Gene 62 Protein antibodyAnti-Mln 62 antibodyAnti-Ring Finger Protein 83 antibodyAnti-TRAF4 CART1 MLN62 RNF83 antibody |
Protein name |
Tnf Receptor-Associated Factor 4Cysteine-Rich Domain Associated With Ring And Traf Domains Protein 1Metastatic Lymph Node Gene 62 ProteinMln 62Ring Finger Protein 83 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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