ArtNr |
STJ28622-50 |
Hersteller |
St John's Laboratory
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Calpain Small Subunit 1 antibody</br>Anti-Css1 antibody</br>Anti-Calcium-Activated Neutral Proteinase Small Subunit antibody</br>Anti-Canp Small Subunit antibody</br>Anti-Calcium-Dependent Protease Small Subunit antibody</br>Anti-Cdps antibody</br>An |
Similar products |
Anti-Calpain Small Subunit 1 antibodyAnti-Css1 antibodyAnti-Calcium-Activated Neutral Proteinase Small Subunit antibodyAnti-Canp Small Subunit antibodyAnti-Calcium-Dependent Protease Small Subunit antibodyAnti-Cdps antibodyAn |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P04632 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 69-268 of human CAPNS1 (NP_001740. 1). |
Short Description |
Rabbit polyclonal against CAPNS1 |
Cellular localization |
CytoplasmCell MembraneTranslocates To The Plasma Membrane Upon Calcium Binding |
Molecular weight |
Calculated: 28kDa. Observed: 28kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:200 |
Alternative names |
Anti-Calpain Small Subunit 1 antibodyAnti-Css1 antibodyAnti-Calcium-Activated Neutral Proteinase Small Subunit antibodyAnti-Canp Small Subunit antibodyAnti-Calcium-Dependent Protease Small Subunit antibodyAnti-Cdps antibodyAnti-Calcium-Dependent Protease Small Subunit 1 antibodyAnti-Calpain Regulatory Subunit antibodyAnti-CAPNS1 CAPN4 CAPNS antibody |
Protein name |
Calpain Small Subunit 1Css1Calcium-Activated Neutral Proteinase Small SubunitCanp Small SubunitCalcium-Dependent Protease Small SubunitCdpsCalcium-Dependent Protease Small Subunit 1Calpain Regulatory Subunit |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
|
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