Anti-SF3B3 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q15393

This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

SF3B3

Rabbit polyclonal against SF3B3

Calculated: 30kDa/44kDa/135kDa. Observed: 136kDa

Anti-Splicing Factor 3b Subunit 3 antibody
Anti-Pre-Mrna-Splicing Factor Sf3b 130 Kda Subunit antibody
Anti-Sf3b130 antibody
Anti-Staf130 antibody
Anti-Spliceosome-Associated Protein 130 antibody
Anti-Sap 130 antibody
Anti-SF3B3 KIAA0017 SAP130 antibody

FOR RESEARCH USE ONLY (RUO).