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Anti-RAB7A antibody

Anti-RAB7A antibody

ArtNr	STJ25267-50
Hersteller	St John's Laboratory
Menge	50ul
Kategorie	Neuroscience Targets for Rodent Neurosciences Antibodies Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Ras-Related Protein Rab-7a antibody</br>Anti-RAB7A RAB7 antibody
Similar products	Anti-Ras-Related Protein Rab-7a antibody Anti-RAB7A RAB7 antibody
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Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P51149
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic/endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
Gene ID	7879
Gene symbol	RAB7A
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 105-207 of human RAB7A (NP_004628. 4).
Short Description	Rabbit polyclonal against RAB7A
Tissue specificity	Widely expressed.high expression found in skeletal muscle.
Cellular localization	Cytoplasmic Vesicle Phagosome Membrane Peripheral Membrane Protein Cytoplasmic Side Late Endosome Membrane Lysosome Membrane Melanosome Membrane Autophagosome Membrane Lipid Droplet Endosome Membrane Colocalizes With Osbpl1a At The Late Endosome Found In The Ruffled Border (A Late Endosomal-Like Compartment In The Plasma Membrane) Of Bone-Resorbing Osteoclasts Recruited To Phagosomes Containing S Aureus Or Mycobacterium Lipid Droplet Localization Is Increased Upon Adrb2 Stimulation
Molecular weight	Calculated: 23kDa. Observed: 23kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Ras-Related Protein Rab-7a antibody Anti-RAB7A RAB7 antibody
Protein name	Ras-Related Protein Rab-7a
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	RAB7A_HUMAN

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