ArtNr |
STJ25267-50 |
Hersteller |
St John's Laboratory
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Ras-Related Protein Rab-7a antibody</br>Anti-RAB7A RAB7 antibody |
Similar products |
Anti-Ras-Related Protein Rab-7a antibodyAnti-RAB7A RAB7 antibody |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P51149 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic/endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 105-207 of human RAB7A (NP_004628. 4). |
Short Description |
Rabbit polyclonal against RAB7A |
Tissue specificity |
Widely expressed.high expression found in skeletal muscle. |
Cellular localization |
Cytoplasmic VesiclePhagosome MembranePeripheral Membrane ProteinCytoplasmic SideLate Endosome MembraneLysosome MembraneMelanosome MembraneAutophagosome MembraneLipid DropletEndosome MembraneColocalizes With Osbpl1a At The Late EndosomeFound In The Ruffled Border (A Late Endosomal-Like Compartment In The Plasma Membrane) Of Bone-Resorbing OsteoclastsRecruited To Phagosomes Containing SAureus Or MycobacteriumLipid Droplet Localization Is Increased Upon Adrb2 Stimulation |
Molecular weight |
Calculated: 23kDa. Observed: 23kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Ras-Related Protein Rab-7a antibodyAnti-RAB7A RAB7 antibody |
Protein name |
Ras-Related Protein Rab-7a |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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