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Anti-PARK7 antibody (1-189) (STJ24895)

Anti-PARK7 antibody (1-189) (STJ24895)

ArtNr	STJ24895-50
Hersteller	St John's Laboratory
Menge	50 ul
Kategorie	Neuroscience Neural Lineage Markers Neuroinflammation Neural Mitochondrial Function Neural Transcription Factors Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Western Blot Immunofluorescence Autophagy Primary Antibodies Glial Cell Markers
Typ	Antibody Polyclonal
Applikationen	WB, IF
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Parkinson Disease Protein 7 antibody</br>Anti-Maillard Deglycase antibody</br>Anti-Oncogene Dj1 antibody</br>Anti-Parkinsonism-Associated Deglycase antibody</br>Anti-Protein Dj-1 antibody</br>Anti-Dj-1 antibody</br>Anti-Protein/Nucleic Acid Deglycase
Similar products	Anti-Parkinson Disease Protein 7 antibody Anti-Maillard Deglycase antibody Anti-Oncogene Dj1 antibody Anti-Parkinsonism-Associated Deglycase antibody Anti-Protein Dj-1 antibody Anti-Dj-1 antibody Anti-Protein/Nucleic Acid Deglycase
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Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	Q99497
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
Gene ID	11315
Gene symbol	PARK7
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-189 of human PARK7 (NP_001116849. 1).
Short Description	Rabbit polyclonal against PARK7
Tissue specificity	Highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart. Detected at slightly lower levels in placenta and brain (at protein level). Detected in astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa. Expressed by pancreatic islets at higher levels than surrounding exocrine tissues.
Cellular localization	Cell Membrane Lipid-Anchor Cytoplasm Nucleus Membrane Raft Mitochondrion Endoplasmic Reticulum Under Normal Conditions Located Predominantly In The Cytoplasm And To A Lesser Extent In The Nucleus And Mitochondrion Translocates To The Mitochondrion And Subsequently To The Nucleus In Response To Oxidative Stress And Exerts An Increased Cytoprotective Effect Against Oxidative Damage Detected In Tau Inclusions In Brains From Neurodegenerative Disease Patients Membrane Raft Localization In Astrocytes And Neuronal Cells Requires Palmitoylation
Molecular weight	Calculated: 19kDa. Observed: 20kDa
Dilution range	WB 1:500-1:2000 IF 1:50-1:200
Alternative names	Anti-Parkinson Disease Protein 7 antibody Anti-Maillard Deglycase antibody Anti-Oncogene Dj1 antibody Anti-Parkinsonism-Associated Deglycase antibody Anti-Protein Dj-1 antibody Anti-Dj-1 antibody Anti-Protein/Nucleic Acid Deglycase Dj-1 antibody Anti-PARK7 antibody
Protein name	Parkinson Disease Protein 7 Maillard Deglycase Oncogene Dj1 Parkinsonism-Associated Deglycase Protein Dj-1 Dj-1 Protein/Nucleic Acid Deglycase Dj-1
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	PARK7_HUMAN

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Menge: 50 ul

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Lieferung vsl. bis 06.09.2024

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