ArtNr |
STJ24076-50 |
Hersteller |
St John's Laboratory
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Haptoglobin antibody</br>Anti-Zonulin Cleaved Into-Haptoglobin Alpha Chain-Haptoglobin Beta Chain antibody</br>Anti-HP antibody |
Similar products |
Anti-Haptoglobin antibodyAnti-Zonulin Cleaved Into-Haptoglobin Alpha Chain-Haptoglobin Beta Chain antibodyAnti-HP antibody |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P00738 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HP (NP_005134. 1). |
Short Description |
Rabbit polyclonal against HP |
Tissue specificity |
Expressed by the liver and secreted in plasma. |
Cellular localization |
Secreted |
Molecular weight |
Calculated: 38kDa/45kDa. Observed: 45kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Haptoglobin antibodyAnti-Zonulin Cleaved Into-Haptoglobin Alpha Chain-Haptoglobin Beta Chain antibodyAnti-HP antibody |
Protein name |
HaptoglobinZonulin Cleaved Into-Haptoglobin Alpha Chain-Haptoglobin Beta Chain |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.