ArtNr |
STJ115870-50 |
Hersteller |
St John's Laboratory
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IF |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Extracellular Superoxide Dismutase Cu-Zn antibody</br>Anti-Ec-Sod antibody</br>Anti-SOD3 antibody |
Similar products |
Anti-Extracellular Superoxide Dismutase Cu-Zn antibodyAnti-Ec-Sod antibodyAnti-SOD3 antibody |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P08294 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 19-160 of human SOD3 (NP_003093. 2). |
Short Description |
Rabbit polyclonal against SOD3 |
Tissue specificity |
Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid. |
Cellular localization |
SecretedExtracellular Space99% Of Ec-Sod Is Anchored To Heparan Sulfate Proteoglycans In The Tissue InterstitiumAnd 1% Is Located In The Vasculature In Equilibrium Between The Plasma And The Endothelium |
Molecular weight |
Calculated: |
Dilution range |
WB 1:500-1:2000 IF 1:50-1:200 |
Alternative names |
Anti-Extracellular Superoxide Dismutase Cu-Zn antibodyAnti-Ec-Sod antibodyAnti-SOD3 antibody |
Protein name |
Extracellular Superoxide Dismutase Cu-ZnEc-Sod |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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