ArtNr |
STJ115525-50 |
Hersteller |
St John's Laboratory
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IF, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Ubiquitin Carboxyl-Terminal Hydrolase 7 antibody</br>Anti-Deubiquitinating Enzyme 7 antibody</br>Anti-Herpesvirus-Associated Ubiquitin-Specific Protease antibody</br>Anti-Ubiquitin Thioesterase 7 antibody</br>Anti-Ubiquitin-Specific-Processing Protea |
Similar products |
Anti-Ubiquitin Carboxyl-Terminal Hydrolase 7 antibodyAnti-Deubiquitinating Enzyme 7 antibodyAnti-Herpesvirus-Associated Ubiquitin-Specific Protease antibodyAnti-Ubiquitin Thioesterase 7 antibodyAnti-Ubiquitin-Specific-Processing Protea |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q93009 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 206-1102 of human USP7 (NP_003461. 2). |
Short Description |
Rabbit polyclonal against USP7 |
Tissue specificity |
Expressed in neural progenitor cells (at protein level). Widely expressed. Overexpressed in prostate cancer. |
Cellular localization |
NucleusCytoplasmPml BodyChromosomePresent In A Minority Of Nd10 Nuclear BodiesAssociation With Icp0/Vmw110 At Early Times Of Infection Leads To An Increased Proportion Of Usp7-Containing Nd10Colocalizes With Atxn1 In The NucleusColocalized With Daxx In Speckled StructuresColocalized With Pml And Pten In Promyelocytic Leukemia Protein (Pml) Nuclear Bodies |
Molecular weight |
Calculated: 126kDa/128kDa. Observed: 138kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 |
Alternative names |
Anti-Ubiquitin Carboxyl-Terminal Hydrolase 7 antibodyAnti-Deubiquitinating Enzyme 7 antibodyAnti-Herpesvirus-Associated Ubiquitin-Specific Protease antibodyAnti-Ubiquitin Thioesterase 7 antibodyAnti-Ubiquitin-Specific-Processing Protease 7 antibodyAnti-USP7 HAUSP antibody |
Protein name |
Ubiquitin Carboxyl-Terminal Hydrolase 7Deubiquitinating Enzyme 7Herpesvirus-Associated Ubiquitin-Specific ProteaseUbiquitin Thioesterase 7Ubiquitin-Specific-Processing Protease 7 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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