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Anti-LRAT antibody

Anti-LRAT antibody

ArtNr	STJ115221-100
Hersteller	St John's Laboratory
Menge	100ul
Kategorie	Antibodies Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Lecithin Retinol Acyltransferase antibody</br>Anti-Phosphatidylcholine--Retinol O-Acyltransferase antibody</br>Anti-LRAT antibody
Similar products	Anti-Lecithin Retinol Acyltransferase antibody Anti-Phosphatidylcholine--Retinol O-Acyltransferase antibody Anti-LRAT antibody
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Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	O95237
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.
Gene ID	9227
Gene symbol	LRAT
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human LRAT (NP_004735. 2).
Short Description	Rabbit polyclonal against LRAT
Tissue specificity	Hepatic stellate cells and endothelial cells (at protein level). Found at high levels in testis and liver, followed by retinal pigment epithelium, small intestine, prostate, pancreas and colon. Low expression observed in brain. In fetal tissues, expressed in retinal pigment epithelium and liver, and barely in the brain.
Cellular localization	Endoplasmic Reticulum Membrane Single-Pass Membrane Protein Rough Endoplasmic Reticulum Endosome Multivesicular Body Cytoplasm Perinuclear Region Present In The Rough Endoplasmic Reticulum And Multivesicular Body In Hepatic Stellate Cells Present In The Rough Endoplasmic Reticulum And Perinuclear Region In Endothelial Cells
Molecular weight	Calculated: 25kDa. Observed: 26-55kDa
Dilution range	WB 1:1000-1:2000 IF 1:50-1:200
Alternative names	Anti-Lecithin Retinol Acyltransferase antibody Anti-Phosphatidylcholine--Retinol O-Acyltransferase antibody Anti-LRAT antibody
Protein name	Lecithin Retinol Acyltransferase Phosphatidylcholine--Retinol O-Acyltransferase
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	LRAT_HUMAN

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Menge: 100ul

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