Anti-HLA-DOB antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P13765

HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.

HLA-DOB

Rabbit polyclonal against HLA-DOB

Calculated: 30kDa. Observed: 36kDa

Anti-Hla Class Ii Histocompatibility Antigen-Do Beta Chain antibody
Anti-Mhc Class Ii Antigen Dob antibody
Anti-HLA-DOB antibody

FOR RESEARCH USE ONLY (RUO).