Anti-CD160 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

O95971

CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1. 5 and 1. 6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.

CD160

Rabbit polyclonal against CD160

Cd160 Antigen: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Cd160 Antigen
Soluble Form: Secreted
Released From The Cell Membrane By Gpi Cleavage

WB 1:500-1:2000

Cd160 Antigen
Natural Killer Cell Receptor By55
Cd Antigen Cd160 Cleaved Into-Cd160 Antigen-Soluble Form

BY55_HUMAN