ArtNr |
STJ110355-50 |
Hersteller |
St John's Laboratory
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Hydroxymethylglutaryl-Coa Lyase-Mitochondrial antibody</br>Anti-Hl antibody</br>Anti-Hmg-Coa Lyase antibody</br>Anti-3-Hydroxy-3-Methylglutarate-Coa Lyase antibody</br>Anti-HMGCL antibody |
Similar products |
Anti-Hydroxymethylglutaryl-Coa Lyase-Mitochondrial antibodyAnti-Hl antibodyAnti-Hmg-Coa Lyase antibodyAnti-3-Hydroxy-3-Methylglutarate-Coa Lyase antibodyAnti-HMGCL antibody |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P35914 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human HMGCL (NP_000182. 2). |
Short Description |
Rabbit polyclonal against HMGCL |
Tissue specificity |
Highest expression in liver. Expressed in pancreas, kidney, intestine, testis, fibroblasts and lymphoblasts. Very low expression in brain and skeletal muscle. The relative expression of isoform 2 (at mRNA level) is highest in heart (30%), skeletal muscle (22%), and brain (14%). |
Cellular localization |
Mitochondrion MatrixPeroxisomeUnprocessed Form Is Peroxisomal |
Molecular weight |
Calculated: 20kDa/26kDa/34kDa. Observed: 30kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:200 |
Alternative names |
Anti-Hydroxymethylglutaryl-Coa Lyase-Mitochondrial antibodyAnti-Hl antibodyAnti-Hmg-Coa Lyase antibodyAnti-3-Hydroxy-3-Methylglutarate-Coa Lyase antibodyAnti-HMGCL antibody |
Protein name |
Hydroxymethylglutaryl-Coa Lyase-MitochondrialHlHmg-Coa Lyase3-Hydroxy-3-Methylglutarate-Coa Lyase |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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