Anti-CHRFAM7A antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q494W8

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.

CHRFAM7A

Rabbit polyclonal against CHRFAM7A

Membrane
Multi-Pass Membrane Protein

WB 1:500-1:2000 IHC 1:50-1:200

Chrna7-Fam7a Fusion Protein
Chrna7-Dr1
D-10

CRFM7_HUMAN