ArtNr |
STJ110154-50 |
Hersteller |
St John's Laboratory
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-Chrna7-Fam7a Fusion Protein antibody</br>Anti-Chrna7-Dr1 antibody</br>Anti-D-10 antibody</br>Anti-CHRFAM7A antibody |
Similar products |
Anti-Chrna7-Fam7a Fusion Protein antibodyAnti-Chrna7-Dr1 antibodyAnti-D-10 antibodyAnti-CHRFAM7A antibody |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q494W8 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human CHRFAM7A (NP_647536. 1). |
Short Description |
Rabbit polyclonal against CHRFAM7A |
Tissue specificity |
Expressed in hippocampus. |
Cellular localization |
MembraneMulti-Pass Membrane Protein |
Molecular weight |
Calculated: 46kDa. Observed: 46kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:200 |
Alternative names |
Anti-Chrna7-Fam7a Fusion Protein antibodyAnti-Chrna7-Dr1 antibodyAnti-D-10 antibodyAnti-CHRFAM7A antibody |
Protein name |
Chrna7-Fam7a Fusion ProteinChrna7-Dr1D-10 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.