ArtNr |
STJ110022-50 |
Hersteller |
St John's Laboratory
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Anti-1-Phosphatidylinositol 4-5-Bisphosphate Phosphodiesterase Gamma-1 antibody</br>Anti-Plc-148 antibody</br>Anti-Phosphoinositide Phospholipase C-Gamma-1 antibody</br>Anti-Phospholipase C-Ii antibody</br>Anti-Plc-Ii antibody</br>Anti-Phospholipase C-Gam |
Similar products |
Anti-1-Phosphatidylinositol 4-5-Bisphosphate Phosphodiesterase Gamma-1 antibodyAnti-Plc-148 antibodyAnti-Phosphoinositide Phospholipase C-Gamma-1 antibodyAnti-Phospholipase C-Ii antibodyAnti-Plc-Ii antibodyAnti-Phospholipase C-Gam |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P19174 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The protein encoded by this gene catalyzes the formation of inositol 1, 4, 5-trisphosphate and diacylglycerol from phosphatidylinositol 4, 5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
A synthetic peptide of human PLCG1 |
Short Description |
Rabbit polyclonal against PLCG1 |
Cellular localization |
Cell ProjectionLamellipodiumRuffleRapidly Redistributed To Ruffles And Lamellipodia Structures In Response To Epidermal Growth Factor (Egf) Treatment |
Molecular weight |
Calculated: 148kDa. Observed: 160kDa |
Dilution range |
WB 1:500-1:2000 IHC 1:50-1:200 |
Alternative names |
Anti-1-Phosphatidylinositol 4-5-Bisphosphate Phosphodiesterase Gamma-1 antibodyAnti-Plc-148 antibodyAnti-Phosphoinositide Phospholipase C-Gamma-1 antibodyAnti-Phospholipase C-Ii antibodyAnti-Plc-Ii antibodyAnti-Phospholipase C-Gamma-1 antibodyAnti-Plc-Gamma-1 antibodyAnti-PLCG1 PLC1 antibody |
Protein name |
1-Phosphatidylinositol 4-5-Bisphosphate Phosphodiesterase Gamma-1Plc-148Phosphoinositide Phospholipase C-Gamma-1Phospholipase C-IiPlc-IiPhospholipase C-Gamma-1Plc-Gamma-1 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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