Mouse Anti-Human CD51-PE

Lot specific

CD51 represents the integrin αV chain that associates with integrin β3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils, and platelets. CD51 is the most promiscuous integrin α subunit as it can form heterodimers with the β1 (CD29), β3 (CD61), β5, β6 and β8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.

Monoclonal

CD51

Purified mouse immunoglobulins

2-8°C; Avoid exposure to light; Do not freeze