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Mouse IL6ST / gp130 / CD130 Protein (His Tag)

Mouse IL6ST / gp130 / CD130 Protein (His Tag)

Hersteller	Sino Biological
Kategorie	Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Targets for Rodent Neurosciences Peptides & Proteins Recombinant Proteins Glial Cell Markers
Typ	Proteins
Specific against	Mouse
Menge	2mg
Host	Human
ArtNr	50135-M08H-2
eClass 6.1	34160400
eClass 9.0	42020190
Lieferbar
Alias	5133400A03Rik, AA389424, BB405851, CD130, D13Ertd699e, gp130
Molecule	IL6ST
Synonym	5133400A03Rik, AA389424, BB405851, CD130, D13Ertd699e, gp130
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the mouse gp130 (NP_034690.3) extracellular domain (Met 1-Glu 617) was fused with a polyhistidine tag at the C-terminus.
Expressed Host	Human Cells
Purity	> 97 % as determined by SDS-PAGE
Bio-Activity	1. Measured by its ability to bind mouse IL11Ra in a functional ELISA. 2. Measured by its ability to inhibit the IL6 Ralpha enhancement of IL6 activity on M1 mouse myeloid leukemia cells (Saito, T. et al. 1991, J. Immunol. 147:168.). The ED50 for this effect is typically 0.6-3 ug/mL in the presence of 10 ng/mL recombinant human IL6 sR and 20 ng/mL recombinant human IL6.
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Glu 19
Molecule Mass	The secreted recombinant mouse gp130 consists of 606 amino acids and has a predicted molecular mass of 68 kDa. As a result of glycosylation, the apparent molecular mass of rm gp130 is approximately 80-90 kDa in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_034690.3
Amino acid sequence	Met1-Glu617
TAG	C-His

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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50135-M08H-2-datasheet.pdf

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