ArtNr |
50059-M03H-2 |
Hersteller |
Sino Biological
|
Menge |
2mg |
Kategorie |
|
Typ |
Proteins |
Specific against |
Mouse |
Host |
Human |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
AI323359, CD115, CSF-1R, Csfmr, Fim-2, Fms, M-CSF-R, M-CSFR |
Similar products |
CSF1R |
Lieferbar |
|
Molecule |
CSF1R |
Synonym |
AI323359, CD115, CSF-1R, Csfmr, Fim-2, Fms, M-CSF-R, M-CSFR |
Storage |
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Protein Construction |
A DNA sequence encoding the mouse CSF1R (Met1-Ser511) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus. |
Expressed Host |
Human Cells |
Purity |
> 95 % as determined by SDS-PAGE |
Bio-Activity |
1. Immobilized mouse CSF1-His (Cat:51112-M08H) at 10 ug/ml (100 ul/well) can bind mouse CSF1R-Fch, The EC50 of mouse CSF1R-Fch is 0.04-0.1 ug/ml. 2. Measured by its ability to inhibit mouse CSF-induced proliferation of M?NFS?60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 0.01-0.04 ug/mL in the presence of 3 ng/ml Recombinant Human M-CSF. |
Endotoxin |
< 1.0 EU per ug of the protein as determined by the LAL method |
Predicted N Terminal |
Ala 20 |
Molecule Mass |
The recombinant mouse CSF1R/Fc is a disulfide-linked homodimer. The reduced monomer comprises 740 amino acids and has a predicted molecular mass of 83.3 kDa. The apparent molecular mass of the protein is approximately 110 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Formulation |
Lyophilized from sterile PBS, pH 7.4 |
Accession |
CSF1R_MOUSE |
Amino acid sequence |
Met1-Ser511 |
TAG |
C-human IgG1-Fc & His |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.