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Mouse CSF1R / MCSF Receptor / CD115 Protein (His & Fc Tag) Europäischer Partner

ArtNr 50059-M03H-2
Hersteller Sino Biological
Menge 2mg
Kategorie
Typ Proteins
Specific against Mouse
Host Human
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias AI323359, CD115, CSF-1R, Csfmr, Fim-2, Fms, M-CSF-R, M-CSFR
Similar products CSF1R
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Molecule
CSF1R
Synonym
AI323359, CD115, CSF-1R, Csfmr, Fim-2, Fms, M-CSF-R, M-CSFR
Storage
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction
A DNA sequence encoding the mouse CSF1R (Met1-Ser511) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
Expressed Host
Human Cells
Purity
> 95 % as determined by SDS-PAGE
Bio-Activity
1. Immobilized mouse CSF1-His (Cat:51112-M08H) at 10 ug/ml (100 ul/well) can bind mouse CSF1R-Fch, The EC50 of mouse CSF1R-Fch is 0.04-0.1 ug/ml.
2. Measured by its ability to inhibit mouse CSF-induced proliferation of M?NFS?60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 0.01-0.04 ug/mL in the presence of 3 ng/ml Recombinant Human M-CSF.
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Ala 20
Molecule Mass
The recombinant mouse CSF1R/Fc is a disulfide-linked homodimer. The reduced monomer comprises 740 amino acids and has a predicted molecular mass of 83.3 kDa. The apparent molecular mass of the protein is approximately 110 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Formulation
Lyophilized from sterile PBS, pH 7.4
Accession
CSF1R_MOUSE
Amino acid sequence
Met1-Ser511
TAG
C-human IgG1-Fc & His

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 2mg
Lieferbar: In stock
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