ArtNr |
10895-H03H-4 |
Hersteller |
Sino Biological
|
Menge |
4mg |
Kategorie |
|
Typ |
Proteins |
Specific against |
Human |
Host |
Human |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
CANDF5, CD217, CDw217, hIL-17R, IL-17RA, IL17R |
Similar products |
IL17RA |
Lieferbar |
|
Molecule |
IL17RA |
Synonym |
CANDF5, CD217, CDw217, hIL-17R, IL-17RA, IL17R |
Storage |
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Protein Construction |
A DNA sequence encoding the extracellular domain of human IL17RA (NP_055154.3) (Met 1-Trp 320) was was fused with the C-terminal polyhistidine-taggged Fc region of human IgG1 at the C-terminus. |
Expressed Host |
Human Cells |
Purity |
> 85 % as determined by SDS-PAGE |
Bio-Activity |
1. Measured by its ability to bind human IL17F in a functional ELISA. 2. Measured by its binding ability in a functional ELISA. 3. Immobilized recombinant human IL17A at 20 ug/ml (100 ul/well) can bind human IL17RA with a linear range of 32-160 ng/ml. |
Endotoxin |
< 1.0 EU per ug of the protein as determined by the LAL method |
Predicted N Terminal |
Leu 33 |
Molecule Mass |
The recombinant human IL17RA/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 536 amino acids and has a predicted molecular mass of 61.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh IL17RA/Fc monomer is approximately 95-105 kDa due to glycosylation. |
Formulation |
Lyophilized from sterile PBS, pH 7.4 |
Accession |
NP_055154.3 |
Amino acid sequence |
Met1-Trp320 |
TAG |
C-human IgG1-Fc & His |
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