Human IGF1 / IGF-I Protein

IGF-1, IGF-I, IGF1A, IGFI, IGF?I, MGF

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

E.coli

1. Measured by its ability to bind human IGFBP4-His (Cat:10967-H08H) in a functional ELISA.
2. Measured by its ability to bind mouse IGFBP4-His (Cat:50250-M08H) in a functional ELISA.
3. Measured by its ability to bind Cynomolgus IGFBP1-His (Cat:90085-C08H) in a functional ELISA.
4. Measured by its ability to bind human IGF1R (aa 954-1367)-GST (Cat:10164-H20B1) in a functional ELISA.
5. Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. The ED50 for this effect is typically 0.5-2 ng/mL.
6. Measured in a cell proliferation assay using MCF-7 cells. The ED50 for this effect is typically 1-4 ng/mL.

Met

Lyophilized from sterile 30% Acetonitrile, 0.1% TFA

Gly49-Ala118