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FGFR4 Protein, Human, Recombinant (hFc Tag)

FGFR4 Protein, Human, Recombinant (hFc Tag)

ArtNr	10538-H02H-100
Hersteller	Sino Biological
Menge	100ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Neural Signaling Neural Adhesion Molecules By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Sarcoma Peptides & Proteins Recombinant Proteins Astrocytoma Calcium Binding Protein Markers
Typ	Proteins
Format	Human Cell
Specific against	Human
Host	Human
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD334, JTK2, TKF
Similar products	FGFR4
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Molecule	FGFR4
Synonym	CD334, JTK2, TKF
Storage	Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction	A DNA sequence encoding the extracellular domain (Met 1-Asp 369) of human FGFR4 (NP_002002.3) precursor was fused with the Fc region of human IgG1 at the C-terminus.
Expressed Host	Human Cells
Purity	> 97 % as determined by SDS-PAGE
Bio-Activity	Measured by its ability to inhibit FGF-acidic (aFGF / FGF1) dependent proliferation of BALB/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 2-6 ng/ml .
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal	Leu 22
Molecule Mass	The recombinant human FGFR4/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 586 amino acids and has a predicted molecular mass of 66 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh FGFR4/Fc monomer is approximately 100-110 kDa due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4
Accession	NP_002002.3
Amino acid sequence	Met1-Asp369
TAG	C-human IgG1-Fc

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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