ArtNr |
10201-H08H-4 |
Hersteller |
Sino Biological
|
Menge |
4mg |
Kategorie |
|
Typ |
Proteins |
Specific against |
Human |
Host |
Human |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
c-erbB-3, c-erbB3, EEBB3, ErbB-3, erbB3-S, HER3, LCCS2, MDA-BF-1, p180-ErbB3, p45-sErbB3, p85-sErbB3 |
Similar products |
ERBB3 |
Lieferbar |
|
Molecule |
ERBB3 |
Synonym |
c-erbB-3, c-erbB3, EEBB3, ErbB-3, erbB3-S, HER3, LCCS2, MDA-BF-1, p180-ErbB3, p45-sErbB3, p85-sErbB3 |
Storage |
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Protein Construction |
A DNA sequence encoding the extracellular domain (Met 1-Thr 643) of human ErbB3 (NP_001973.2) precursor was expressed, with a C-terminal polyhistidine tag. |
Expressed Host |
Human Cells |
Purity |
> 95 % as determined by SDS-PAGE |
Bio-Activity |
1. Measured by its binding ability in a functional ELISA. 2. Immobilized human ErbB3 at 2 ug/mL (100 ul/well) can bind human NRG1 (isoform Beta1), The EC50 of human NRG1 (isoform Beta1) is 0.43 ug/mL. |
Endotoxin |
< 1.0 EU per ug of the protein as determined by the LAL method |
Predicted N Terminal |
Ser 20 |
Molecule Mass |
The recombinant human ErbB3 protein consists of 635 amino acids after the removal of signal peptide and has a calculated molecular mass of 70.2 kDa. As a result of glycosylation, the recombinant ErbB3 migrates as an approximately 100-110 kDa band in SDS-PAGE under reducing conditions. |
Formulation |
Lyophilized from sterile PBS, pH 7.5 |
Accession |
NP_001973.2 |
Amino acid sequence |
Met1-Thr643 |
TAG |
C-His |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.