ArtNr |
10161-H03H-100 |
Hersteller |
Sino Biological
|
Menge |
100ug |
Kategorie |
|
Typ |
Proteins |
Format |
Human Cell |
Specific against |
Human |
Host |
Human |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R, MCSF Receptor |
Similar products |
CSF1R |
Lieferbar |
|
Molecule |
CSF1R |
Synonym |
C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R, MCSF Receptor |
Storage |
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Protein Construction |
A DNA sequence encoding the extracellular domain (Met 1-Glu512) of human M-CSFR (NP_005202.2) precursor was expressed with the fused C-terminal polyhistide-tagged Fc region of human IgG1 at the C-terminus. |
Expressed Host |
Human Cells |
Purity |
> 95 % as determined by SDS-PAGE |
Bio-Activity |
1. Measured by its ability to bind biotinylated Human CSF1-his in functional ELISA. 2. Measured by its ability to inhibit the human CSF-induced proliferation of M?NFS?60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 0.1-0.6 ug/mL in the presence of 3 ng/ml Recombinant Human M-CSF. |
Endotoxin |
< 1.0 EU per ug of the protein as determined by the LAL method |
Predicted N Terminal |
Ile 20 |
Molecule Mass |
The recombinant human M-CSFR/Fc chimera is a disulfide-linked homodimer protein. The monomeric subunit contains 737 amino acids after the removal of signal peptide with a calculated molecular mass of 82.4 kDa. As a result of glycosylation, the monomer migrates as an approximately 115-125 kDa protein in SDS-PAGE under reducing conditions. |
Formulation |
Lyophilized from sterile PBS, pH 7.4 |
Accession |
NP_005202.2 |
Amino acid sequence |
Met1-Glu512 |
TAG |
C-human IgG1-Fc & His |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.