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Human EGFR Phosphorylation Array C1

Human EGFR Phosphorylation Array C1

ArtNr	AAH-PER-1-4
Hersteller	Raybiotech
Menge	4 Sample Kit
Quantity options	2 Sample Kit 4 Sample Kit 8 Sample Kit
Kategorie	Oncology Neuroscience Neural Adhesion Molecules By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Arrays By Organ Lung Cancer Bladder Cancer Colorectal Cancer Breast Cancer Testicular & Prostate Cancer Antibody Arrays
Typ	Array
Specific against	Human (Homo sapiens)
Host	Hamster - Armenian
Citations	1. Shalaby A., et al. The role of epidermal growth factor receptor in chordoma pathogenesis: a potential therapeutic target. J Pathol. 2011 Feb,223(3):336-46. doi: 10.1002/path.2818. 2. Bhuvaneswari R., et al. Targeting EGFR with photodynamic therapy in combination with Erbitux enhances in vivo bladder tumor response., Mol Cancer. 2009 Nov 2,8:94. doi: 10.1186/1476-4598-8-94. 3. Zhu S., et al. DARPP-32 Increases Interactions Between Epidermal Growth Factor Receptor and ERBB3 to Promote Tumor Resistance to Gefitinib. Gastroenterology. 2011 Nov,141(5):1738-48.e1-2. doi: 10.1053/j.gastro.2011.06.070. 4. Cheng KW, Wong CC, Alston N, et al. Aerosol administration of phospho-sulindac inhibits lung tumorigenesis. Mol. Cancer Ther. 2013 May 3, 12: 1417-1428
ECLASS 10.1	32161000
ECLASS 11.0	32161000
UNSPSC	41116126
Similar products	EGFR (Tyr845), EGFR (Tyr992), EGFR (Tyr1045), EGFR (Tyr1068), EGFR (Tyr1086), EGFR(Tyr1148), EGFR (Tyr1173), EGFR (Ser1046/1047), EGFR (Ser1070), ErbB2 (Tyr877), ErbB2 (Tyr1112), ErbB2 (Tyr 1221/1222), ErbB2 (Tyr1248), ErbB2 (Thr686), ErbB2 (Ser1113), ErbB3 (Tyr1289), ErbB4 (Tyr1284)
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Category	Arrays\|Post-Translational Modification Arrays\|Phosphorylation Arrays\|Antibody Arrays\|Membrane Antibody Arrays
Manufacturer - Targets	EGFR (P-Ser1046/1047), EGFR (P-Ser1070), EGFR (P-Tyr1045), EGFR (P-Tyr1068), EGFR (P-Tyr1086), EGFR (P-Tyr1148), EGFR (P-Tyr1173), EGFR (P-Tyr845), EGFR (P-Tyr992), ErbB1 (P-Ser1046/1047), ErbB1 (P-Ser1070), ErbB1 (P-Tyr1045), ErbB1 (P-Tyr1068), ErbB1 (P-Tyr1086), ErbB1 (P-Tyr1148), ErbB1 (P-Tyr1173), ErbB1 (P-Tyr845), ErbB1 (P-Tyr992), ErbB2 (P-Ser1113), ErbB2 (P-Thr686), ErbB2 (P-Tyr 1221/1222), ErbB2 (P-Tyr1112), ErbB2 (P-Tyr1248), ErbB2 (P-Tyr877), ErbB3 (P-Tyr1289), ErbB4 (P-Tyr1284)
Shipping Temperature	Blue ice
Storage Conditions	-20°C
Description	C-Series Human EGFR Phosphorylation Antibody Array 1 Kit. Detects 16 site specific and pan Human EGFRs. Suitable for all liquid sample types but intended for use with cell and tissue lysates.
Number of Targets Detected	17
Compatible Sample Types	Cell Culture Supernatants, Plasma, Serum, Tissue Lysates, Cell Lysates
Design Principle	Sandwich-based
Method of Detection	Chemiluminescence
Solid Support	Membrane
Kit Components	Human EGFR Phosphorylation Antibody Array C1 Membranes Blocking Buffer Wash Buffer 1 Wash Buffer 2 Biotinylated Detection Antibody Cocktail Streptavidin-Conjugated HRP Detection Buffer C Detection Buffer D Lysis Buffer Protease Inhibitor Cocktail Phosphatase Inhibitor Cocktail Set I Phosphatase Inhibitor Cocktail II 8-Well Incubation Tray Plastic Sheets Array Templates Manual
Other Materials Required	Pipettors, pipet tips and other common lab consumables Orbital shaker or oscillating rocker Tissue Paper, blotting paper or chromatography paper Adhesive tape or Saran Wrap Distilled or de-ionized water A chemiluminescent blot documentation system (such as UVPs ChemiDoc-It or EpiChem II Benchtop Darkroom), X-ray Film and a suitable film processor, or another chemiluminescent detection system.
Protocol Outline	Block membranes Incubate with Sample Incubate with Biotinylated Detection Antibody Cocktail Incubate with HRP-Conjugated Streptavidin Incubate with Detection Buffers Image with chemiluminescent imaging system Perform densitometry and analysis
Product Features	Easy to use No specialized equipment needed Compatible with nearly any liquid sample Proven technology (many publications) Highly sensitive (pg/ml) Sandwich ELISA specificity Higher density than ELISA, Western blot or bead-based multiplex
Result Output	Semi-Quantitative
UNSPSC Code	41116133

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