ArtNr |
AAH-APO-1-4 |
Hersteller |
Raybiotech
|
Menge |
4 Sample Kit |
Quantity options |
2 Sample Kit
4 Sample Kit
8 Sample Kit
|
Kategorie |
|
Typ |
Array |
Specific against |
Human (Homo sapiens) |
Host |
Hamster - Armenian |
Citations |
1. Spadavecchia S, Gonzalez-Lopez OD, Kyla Driscoll Carroll KD, Diana Palmeri D, Lukac DM. Convergence of KSHV Reactivation with EBV latency and cellular growth mediated by the Notch signaling pathway in co-infected cells. J Virol. 2010:84(20):10488–15000. 2. Malla R., et al. Downregulation of uPAR and Cathepsin B Induces Apoptosis via Regulation of Bcl-2 and Bax and Inhibition of the PI3K/Akt Pathway in Gliomas. PLOS One. Published: October 29, 2010 DOI: 10.1371/journal.pone.0013731 3. Rahabi-Layachi H., et al. You have full text access to this content Distinct effects of inorganic phosphate on cell cycle and apoptosis in human vascular smooth muscle cells. J of Cell Phys. Accepted manuscript online: 27 JUN 2014. | DOI: 10.1002/jcp.24715 4. Wu J., et al. Blocking the bFGF/STAT3 interaction through specific signaling pathways induces apoptosis in glioblastoma cells. J Neurooncol publihsed online July 2014. DOI 10.1007/s11060-014-1529-8 5. Lattuada D., et al. Proapoptotic Activity of a Monomeric Smac Mimetic on Human Fibroblast-Like Synoviocytes from Patients with Rheumatoid Arthritis. Inflammation, Sept 2014, epub ahead of print. DOI: 10.1007/s10753-014-0012-1 6. Paydar, M., Kamalidehghan, B. et al. evaluation of cytotoxic and chemotherapeutic properties of boldine in breast cancer using in vitro and in vivo models. Drug Design, Development and Therapy, Volume 2014:8 Pages 719 - 733. June 2014 7. Karimian H., et al. Ferulago angulata activates intrinsic pathway of apoptosis in MCF-7 cells associated with G1 cell cycle arrest via involvement of p21/p27. Drug Design, Development and Therapy, Sept 2014, epub ahead of print.http://dx.doi.org/10.2147/DDDT.S68818 |
ECLASS 10.1 |
32161000 |
ECLASS 11.0 |
32161000 |
UNSPSC |
41116126 |
Similar products |
p53, Survivin, IGFBP-5, p21, p27, IGFBP-2, BID, XIAP, CD40, DR6, Fas, HSP70, IGF-1, CD40 Ligand, HSP60, BIM, HTRA, HSP27, IGFBP-1, TNF beta, TNF alpha, IGFBP-3, Fas Ligand, Caspase 8, Caspase 3, IGF-2, TRAIL R1, TRAIL R4, bax, SMAC, IGFBP-4, bcl-w, TRAIL R2, TRAIL R3, sTNFRI, sTNFRII, IGFBP-6, cIAP-2, bcl-2, bad, Cytochrome-C, IGF-1sR, livin |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Manufacturer - Applications |
Multiplexed Protein Detection Detection of Relative Protein Expression Detecting Patterns of Cytokine Expression Biomarker/ Key Factor Screening Identifying Key Factors Confirming a Biological Process |
Manufacturer - Category |
Arrays|Apoptosis Arrays|Cytokine Arrays|Antibody Arrays|Membrane Antibody Arrays |
Shipping Temperature |
Blue ice |
Storage Conditions |
-20°C |
Number of Targets Detected |
43 |
Compatible Sample Types |
Cell Culture Supernatants Cell Lysates Plasma Serum Tissue Lysates |
Design Principle |
Sandwich-based |
Method of Detection |
Chemiluminescence |
Quantitative/Semi-Quantitative |
Semi-Quantitative |
Solid Support |
Membrane |
Gene Symbols |
BAD | BAX | BCL2 | BCL2L11 | BCL2L2 | BID | BIRC3 | BIRC5 | BIRC7 | CASP3| CASP8 | CD40 | CD40LG | CDKN1A | CYCS | DIABLO | FAS | FASLG | HSPA14 | HSPA4 | HSPB1 | HTRA2 | IGF1 | IGF1R | IGF2 | IGFBP1 | IGFBP2 | IGFBP3 | IGFBP4 | IGFBP5 | IGFBP6 | LTA | SSSCA1 | TNF | TNFRSF10A | TNFRSF10B | TNFRSF10C | TNFRSF10D | TNFRSF1A | TNFRSF1B | TNFRSF21 | TP53 | XIAP |
Kit Components |
Human Apoptosis Antibody Array C1 Membranes Blocking Buffer Wash Buffer 1 Wash Buffer 2 Biotinylated Detection Antibody Cocktail Streptavidin-Conjugated HRP Detection Buffer C Detection Buffer D Lysis Buffer Protease Inhibitor Cocktail8-Well Incubation Tray Plastic Sheets Array Templates Manual |
Other Materials Required |
Pipettors, pipet tips and other common lab consumables Orbital shaker or oscillating rocker Tissue Paper, blotting paper or chromatography paper Adhesive tape or Saran Wrap Distilled or de-ionized water A chemiluminescent blot documentation system (such as UVP's Chemi Doc-It® or Epi Chem I I Benchtop Darkroom or G E's Image Quant„¢ LAS 4000 or Amersham Imagers 600 and 680), X-ray Film and a suitable film processor, or another chemiluminescent detection system. |
Protocol Outline |
Block membranes Incubate with Sample Incubate with Biotinylated Detection Antibody Cocktail Incubate with HRP-Conjugated Streptavidin Incubate with Detection Buffers Image with chemiluminescent imaging system Perform densitometry and analysis |
Product Features |
Easy to use No specialized equipment needed Compatible with nearly any liquid sample Proven technology (many publications) Highly sensitive (pg/ml) Sandwich ELISA specificity Higher density than ELISA, Western blot or bead-based multiplex |
UNSPSC Code |
41116133 |
Pathway |
Akt SignalingIGF Signalingp53 Signaling |