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Rabbit Anti-Human CART

Rabbit Anti-Human CART

ArtNr	RB-08-0012-100
Hersteller	Raybiotech
Menge	100 ug
Kategorie	Antibodies ELISA Primary Antibodies
Typ	Antibody
Format	Supplied as 200 ug of purified and lyophilized antibody. The antibody is stable for at least one year from the data of receipt when stored at -20C to -70C. Reconstituted antibody (suggesting with sterile PBS) can also be aliquotted and stored frozen at -2
Applikationen	ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CART
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Target Name	CART
Accession Number	CAG47012
Conjugate/Tag/Label	Biotin
Application notes:	ELISA (recommended work dilution= 1:10e6(at least detecting 2-5ng/ml)), Western Blotting (recommended work dilution= 1:1000-5000(at least))
Product Description	The neuropeptide, Cocaine and Amphetamine Regulated Transcript (CART), was identified as an mRNA that changed in response to psychostimulant drug administration and injection of CART peptides into the ventral tegmental area produces psychostimulant-like effects. CART encodes for a protein which has an important role in the regulation of appetite and body weight. CART localizes to areas of the central and peripheral nervous systems and is involved in feeding behavior when injected centrally. Expression of CART in the rat hypothalamus is modulated by nutritional status, and injection of synthetic CART peptide into the forebrain ventricular system suppresses food intake, indicating a possible role in hypothalamic control of energy homeostasis. Its identification in cell bodies and central terminals of vagal afferent neurons additionally suggests a role in brainstem mechanisms of meal termination and satiety.
Immunogen	Immunogen was synthetic peptide derived from Human Cart. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbitt serum by ammonium sulphate precipitation followed by Protein A/G affinity chromatography.

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