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Rabbit Anti-Human GHRL

Rabbit Anti-Human GHRL

ArtNr	RB-08-0001-100
Hersteller	Raybiotech
Menge	100 ug
Kategorie	Antibodies ELISA Primary Antibodies
Typ	Antibody
Format	Supplied as 200 ug of purified and lyophilized antibody. The antibody is stable for at least one year from the data of receipt when stored at -20C to -70C. Reconstituted antibody (suggesting with sterile PBS) can also be aliquotted and stored frozen at -2
Applikationen	ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	GHRL
Lieferbar
Target Name	GHRL
Accession Number	NM_016362
Conjugate/Tag/Label	Biotin
Application notes:	ELISA (recommended work dilution= 1:10e4), Western Blotting (recommended work dilution= 1:1000-2000)
Product Description	Ghrelin is synthesized as a preprohormone, and then proteolytically processed to yield a 28-amino acid peptide. It is a recently isolated brain-gut peptide that has growth hormone-releasing and appetiteinducing activities. Several recent studies have suggested that ghrelin plays a major role in the pathophysiology of drug-seeking behavior and anxiety. The rat and human mature Ghrelin (28-aa) are produced from 117 amino acids precursor peptides that have a signal peptide followed by the ghrelin sequence. At the C-terminus of the ghrelin sequence, processing occurs at an uncommon Pro-Arg recognition site. In rat stomach, two isoforms of mRNA for pro-ghrelin are produced from the gene by an alternative splicing. One mRNA encodes the ghrelin precursor, and another encodes a des-Gln14- ghrelin precursor. O-octanoylation or O-decanoylation is essential for ghrelin activity. The Odecanoylated forms Ghrelin-27-C10 and Ghrelin-28-C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26.
Immunogen	Immunogen was synthetic peptide derived from Human Ghrelin precursor. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum by ammonium sulphate precipitation followed by Protein A/G affinity chromatography.

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