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Mouse Anti-Human AR

Mouse Anti-Human AR

ArtNr	130-10083-100
Hersteller	Raybiotech
Menge	100 ug
Kategorie	Oncology Antibodies ELISA Primary Antibodies By Organ Breast Cancer Heart & Blood Cancer
Typ	Antibody
Format	Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile 1 x PBS to a final concentration of 1 mg/ml.
Applikationen	ELISA
Specific against	Human
Host	Mouse
Isotype	IgG1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	AR
Lieferbar
Target Name	AR
Accession Number	NP_000035
Application notes:	ELISA (recommended work dilution= 6.25 ng/ml ), Western Blotting (recommended work dilution= 1:2000 ), (see image) Immunodetection Analysis: Representative blot from a previous lot. Lane 1, protein BSA, Lane 2, recombinant protein AR, Lane 3, protein marker. The membrane blot was probed with anti-AR primary antibody (0.5ug/ ml). Proteins were visualized using a Donkey anti-mouse secondary antibody conjugated to IRDye 800CW detection system.
Product Description	The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression. However, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.
Immunogen	Immunogen was recombinant protein derived from AR. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.

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