Vergleich

Anti-TOP3B Rabbit mAb

ArtNr PTM-7110
Hersteller PTM Biolabs
Menge 100 ul
Format Lyophilized powder
Applikationen WB, ICC
Clon JRMR-10725-50
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
Alias DNA topoisomerase 3 beta 1, DNA topoisomerase III beta 1, TOP3B1
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Uncategorized
Manufacturer - Targets
TOP3B
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Manufacturer - Research Area
Epigenetics
Product description
DNA topoisomerase 3-beta-1(TOP3B), an enzyme that controls and alters the topologic states of DNA during transcription. TOP3B catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. TOP3B interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of TOP3B may be related to higher survival rates in breast cancer patients.
Purification Method
Protein A purified
Constituents
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Recombinant Monoclonal
Stability
Stable for 12 months from date of receipt/reconstitution.
Background
DNA topoisomerase 3-beta-1(TOP3B), an enzyme that controls and alters the topologic states of DNA during transcription. TOP3B catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. TOP3B interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of TOP3B may be related to higher survival rates in breast cancer patients.
Cellular Localization
Nucleus

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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