Anti-LYRIC/AEG1 Rabbit mAb

Primary Antibodies

LYRIC/AEG1

Store at -20°C. Avoid freeze/thaw cycles.

Astrocyte Elevated Gene 1 (AEG-1 ), also named as Lyric or MTDH, was identified as a tight junction (TJ) protein based on its localization to TJ proteins in polarized epithelium.Differential subcellular localization and overexpression of AEG-1 has been seen in multiple human cancers. AEG-1 is involved in signaling pathways related to various cellular functions including proliferation and apoptosis/survival, and its alteration in cancer is associated with poor prognosis. In breast cancer, increased AEG-1 may confer increased chemoresistance as well as metastasis AEG-1 expression is important in signaling and disease progression of hepatocellular carcinoma (HCC) and glioblastoma multiforme (GBM).

PBS, Glycerol, BSA

Recombinant Monoclonal

Astrocyte Elevated Gene 1 (AEG-1 ), also named as Lyric or MTDH, was identified as a tight junction (TJ) protein based on its localization to TJ proteins in polarized epithelium.Differential subcellular localization and overexpression of AEG-1 has been seen in multiple human cancers. AEG-1 is involved in signaling pathways related to various cellular functions including proliferation and apoptosis/survival, and its alteration in cancer is associated with poor prognosis. In breast cancer, increased AEG-1 may confer increased chemoresistance as well as metastasis AEG-1 expression is important in signaling and disease progression of hepatocellular carcinoma (HCC) and glioblastoma multiforme (GBM).