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Anti-RPS3 Rabbit mAb

ArtNr PTM-7068
Hersteller PTM Biolabs
Menge 100 ul
Format Lyophilized powder
Applikationen WB
Clon JRMR-10797-14
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
Alias 40S ribosomal protein S3
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Uncategorized
Manufacturer - Targets
RPS3
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Manufacturer - Research Area
Cell Biology, Epigenetics
Product description
Ribosomal protein S3 (RPS3) is a component of the 40S ribosomal subunit and is involved in translation. HSP90 interacts with both the amino-terminus and carboxy-terminus of RPS3, preventing its ubiquitination and degradation and thereby retaining the integrity of the ribosome. RPS3 has also been shown to function as an endonuclease during DNA damage repair. Furthermore, overexpression of RPS3 sensitizes lymphocytic cells to cytokine-induced apoptosis, indicating a third role for RPS3 during apoptosis.
Purification Method
Protein A purified
Constituents
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Recombinant Monoclonal
Stability
Stable for 12 months from date of receipt/reconstitution.
Background
Ribosomal protein S3 (RPS3) is a component of the 40S ribosomal subunit and is involved in translation. HSP90 interacts with both the amino-terminus and carboxy-terminus of RPS3, preventing its ubiquitination and degradation and thereby retaining the integrity of the ribosome. RPS3 has also been shown to function as an endonuclease during DNA damage repair. Furthermore, overexpression of RPS3 sensitizes lymphocytic cells to cytokine-induced apoptosis, indicating a third role for RPS3 during apoptosis.
Cellular Localization
Cytoplasm

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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