Vergleich

Anti-CXCR5 Rabbit pAb

ArtNr PTM-6901
Hersteller PTM Biolabs
Menge 100 ul
Format Lyophilized powder
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
Alias C-X-C chemokine receptor type 5, CXC-R5, CXCR-5, MDR-15, CD185, BLR1
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Uncategorized
Manufacturer - Targets
CXCR5
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Manufacturer - Research Area
Cardiovascular Biology, Immunology, Signal Transduction, Microbiology, Cancer, Neuroscience
Product description
CXCR5 is a G protein-coupled receptor belonging to the chemokine receptor subfamily. Upon binding of its ligand, the chemokine CXCL13, CXCR5 initiates multiple intracellular signaling pathways that regulate cell proliferation, survival, and migration. CXCR5 is expressed in both mature B cells and follicular helper T cells, and respond to CXCL13 gradient to control lymphocyte migration towards secondary lymphoid tissues. CXCR5 has also been shown to be highly expressed in primary breast tumors, in correlation with their propensity to grow and metastasize.
Purification Method
Protein A purified
Constituents
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Polyclonal
Stability
Stable for 12 months from date of receipt/reconstitution.
Background
CXCR5 is a G protein-coupled receptor belonging to the chemokine receptor subfamily. Upon binding of its ligand, the chemokine CXCL13, CXCR5 initiates multiple intracellular signaling pathways that regulate cell proliferation, survival, and migration. CXCR5 is expressed in both mature B cells and follicular helper T cells, and respond to CXCL13 gradient to control lymphocyte migration towards secondary lymphoid tissues. CXCR5 has also been shown to be highly expressed in primary breast tumors, in correlation with their propensity to grow and metastasize.
Cellular Localization
Membrane

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
lieferbar

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