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Anti-PPT1 Mouse mAb

Anti-PPT1 Mouse mAb

ArtNr	PTM-6854
Hersteller	PTM Biolabs
Menge	100 ul
Format	Lyophilized powder
Applikationen	WB
Clon	10732
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Konjugat/Tag	Unconjugated
Alias	CLN1, PPT, Palmitoyl-protein thioesterase 1
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Uncategorized
Manufacturer - Targets	PPT1
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Manufacturer - Research Area	Signal Transduction, Neuroscience
Product description	The defective gene behind the INCL(infantile neuronal ceroid lipofuscinoses) disease, CLN1, encodes for palmitoyl protein thioesterase 1 (PPT1). It consists of 306 amino acids, including a signal sequence of 26 amino acids and three N-linked glycosylation sites. This protein exists with the molecular mass of 32 kDa, 34 kDa, 36 kDa and 38 kDa. The enzyme is transported into lysosomes of non-neuronal cells by the mannose 6-phosphate receptor (M6PR) mediated pathway and a significant amount of native PPT1 resides in a complex rather than in a monomeric form.
Purification Method	Protein A purified
Constituents	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Recombinant Monoclonal
Stability	Stable for 12 months from date of receipt/reconstitution.
Background	The defective gene behind the INCL(infantile neuronal ceroid lipofuscinoses) disease, CLN1, encodes for palmitoyl protein thioesterase 1 (PPT1). It consists of 306 amino acids, including a signal sequence of 26 amino acids and three N-linked glycosylation sites. This protein exists with the molecular mass of 32 kDa, 34 kDa, 36 kDa and 38 kDa. The enzyme is transported into lysosomes of non-neuronal cells by the mannose 6-phosphate receptor (M6PR) mediated pathway and a significant amount of native PPT1 resides in a complex rather than in a monomeric form.
Cellular Localization	Lysosome, Secreted

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Menge: 100 ul

lieferbar

Lieferung vsl. bis 17.01.2025

Express-Lieferung: 1 Tage sparen

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