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Anti-TNF Receptor II Rabbit mAb

Anti-TNF Receptor II Rabbit mAb

ArtNr	PTM-6834
Hersteller	PTM Biolabs
Menge	100 ul
Format	Lyophilized powder
Applikationen	WB, ICC, IHC-P
Clon	JMMR-3528
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG Kappa
Konjugat/Tag	Unconjugated
Alias	TNFRSF1B, TNFBR, TNFR2
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Uncategorized
Manufacturer - Targets	TNF receptor II
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Manufacturer - Research Area	Cell Biology, Immunology, Signal Transduction, Cancer, Cardiovascular Biology, Neuroscience
Product description	TNF receptor II (TNF-R2) is one of the receptors of TNF-α. The two receptors for TNF-α, TNF-R1 (55 kDa) and TNF-R2 (75 kDa), can mediate distinct cellular responses. In most cases, cytotoxicity elicited by TNF has been reported to act through TNF-R1. In contrast, TNF-R2 appears to be important in T cell signaling and responses to infection. TNF-R2 binds to distinct members of the TRAF family, leading to the activation of NF-κB. Soluble forms of both receptors have also been characterized which can bind TNF-α and may play an important role in immune disorders.
Purification Method	Protein A purified
Constituents	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Recombinant Monoclonal
Stability	Stable for 12 months from date of receipt/reconstitution.
Background	TNF receptor II (TNF-R2) is one of the receptors of TNF-α. The two receptors for TNF-α, TNF-R1 (55 kDa) and TNF-R2 (75 kDa), can mediate distinct cellular responses. In most cases, cytotoxicity elicited by TNF has been reported to act through TNF-R1. In contrast, TNF-R2 appears to be important in T cell signaling and responses to infection. TNF-R2 binds to distinct members of the TRAF family, leading to the activation of NF-κB. Soluble forms of both receptors have also been characterized which can bind TNF-α and may play an important role in immune disorders.
Cellular Localization	Cell membrane, Secreted

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Einfache Bestellung Periodische Bestellung

Menge: 100 ul

lieferbar

Lieferung vsl. bis 17.01.2025

Express-Lieferung: 1 Tage sparen

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