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Anti-Bcr Rabbit mAb

Anti-Bcr Rabbit mAb

ArtNr	PTM-6793
Hersteller	PTM Biolabs
Menge	100 ul
Format	Lyophilized powder
Applikationen	WB, IHC-P
Clon	JMMR-3377
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG Kappa
Konjugat/Tag	Unconjugated
Alias	Breakpoint cluster region protein, BCR1, D22S11
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Uncategorized
Manufacturer - Targets	Bcr
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Manufacturer - Research Area	Signal Transduction, Neuroscience, Cancer
Product description	Break point cluster region protein (Bcr) is encoded by the Bcr gene. The Bcr gene, mapping on chromosome22, was orginally identified by its presence in the chimeric Bcr-Abl oncogene. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine / threonine kinase activity and is a GTPase-activating protein for RAC1 and CDC42. A chromosomal aberration involving BCR has been found in patients with chronic myeloid leukemia.
Purification Method	Protein A purified
Constituents	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Recombinant Monoclonal
Stability	Stable for 12 months from date of receipt/reconstitution.
Background	Break point cluster region protein (Bcr) is encoded by the Bcr gene. The Bcr gene, mapping on chromosome22, was orginally identified by its presence in the chimeric Bcr-Abl oncogene. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine / threonine kinase activity and is a GTPase-activating protein for RAC1 and CDC42. A chromosomal aberration involving BCR has been found in patients with chronic myeloid leukemia.
Cellular Localization	Synapse, dendritic spine, axon

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

lieferbar

Lieferung vsl. bis 17.01.2025

Express-Lieferung: 1 Tage sparen

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