ArtNr |
PTM-6760 |
Hersteller |
PTM Biolabs
|
Menge |
100 ul |
Format |
Lyophilized powder |
Applikationen |
WB |
Clon |
JRMR-10704-13B |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus) |
Host |
Rabbit |
Isotype |
IgG |
Konjugat/Tag |
Unconjugated |
Alias |
P2Y15, P2Y-like GPCR, P2Y-like nucleotide receptor, GPR80, P2RY15 |
Versandbedingung |
Raumtemperatur |
Lieferbar |
|
Manufacturer - Type |
Primary Antibodies |
Manufacturer - Category |
Uncategorized |
Manufacturer - Targets |
OXGR1/GPR99 |
Shipping Temperature |
Ambient temperature |
Storage Conditions |
Store at -20°C. Avoid freeze/thaw cycles. |
Manufacturer - Research Area |
Signal Transduction |
Product description |
OXGR1 is a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily. The encoded protein is activated by the citric acid intermediate, oxoglutarate, as well as several cysteinyl leukotrienes, including leukotrienes E4, C4 and D4, which are implicated in many inflammatory disorders. In mice, a knock-out of this gene leads to middle ear inflammation, changes in the mucosal epithelium, and an increase in fluid behind the eardrum, and is associated with hearing loss. |
Purification Method |
Protein A purified |
Constituents |
PBS, Glycerol, BSA |
PTM |
Unmodified |
Clonality |
Recombinant Monoclonal |
Stability |
Stable for 12 months from date of receipt/reconstitution. |
Background |
OXGR1 is a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily. The encoded protein is activated by the citric acid intermediate, oxoglutarate, as well as several cysteinyl leukotrienes, including leukotrienes E4, C4 and D4, which are implicated in many inflammatory disorders. In mice, a knock-out of this gene leads to middle ear inflammation, changes in the mucosal epithelium, and an increase in fluid behind the eardrum, and is associated with hearing loss. |
Cellular Localization |
Membrane |
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