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Biotinylated Human Latent TGF beta 1/TGFB1 Protein (TG1-HM401B)

ArtNr TG1-HM401B-500UG
Hersteller KactusBio
Menge 500 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against Human
Host HEK293
Konjugat/Tag Biotin, Avi, HIS
Purity > 95% as determined by Tris-Bis PAGE;> 93% as determined by HPLC
Formula Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.
Sequence Leu30-Ser390(C33S)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CEDLAP; DPD1; TGF beta1; TGFB; TGFB1; TGFbeta; TGF-beta-1
Lieferbar
Description
Recombinant Biotinylated Human Latent TGF beta 1/TGFB1 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Leu30-Ser390(C33S).
Background
Latent TGF beta 1 cDNA encodes a 390 amino acid precursor that contains a 29 aa signal peptide and a 361 aa proprotein. A furin‑like convertase processes the proprotein to generate an N‑terminal 249 aa latency‑associated peptide (LAP) and a C‑terminal 112 aa mature TGF‑ beta 1. Disulfide‑linked homodimers of LAP and TGF‑ beta 1 remain non‑covalently associated after secretion, forming the small latent TGF‑ beta 1 complex.
Manufacturers Product Type
Recombinant Protein
Endotoxin
Less than 1EU per μg by the LAL method.
Molecular Weight
The protein has a predicted MW of 44.2 kDa. Due to glycosylation, the protein migrates to 40-50 (LAP) /13-15 (Mature TGF beta 1) kDa based on Tris-Bis PAGE result.
Stability and Storage
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Tag Information
N-His-Avi, Biotin
Formulation
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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