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Human Syndecan-1 Protein, Fc Tag Europäischer Partner

ArtNr SY1-H5253-100ug
Hersteller ACROBiosystems
Menge 100 ug
Kategorie
Typ Proteins Recombinant
Format Powder
Specific against Human
Host HEK293
Konjugat/Tag Unconjugated, Fc
Purity 95%
Citations (1) Butler B, et al. 2015. J Biol Chem. 290(49):29542-54. (2) Logan T, 2017. Nat Neurosci. 20(5):681-689. (3) Huang CC, et al. 2018. J Cell Sci. 131(23). (4) Burre J, et al. 2010. Science. 329(5999):1663-7.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias SDC1,Syndecan-1,CD138,SYND1,SDC
Lieferbar
Manufacturers Category
Protein / Bio-Markers & CD Antigens
Description
Human Syndecan-1, Fc Tag (SY1-H5253) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Gly 254 (Accession # P18827-1).
Molecule
Syndecan-1
Exp Region
Gln 23 - Gly 254
Storage
-20℃
Shipping
RT
Stability
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight
50.3 kDa
Characteristics
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.3 kDa. The protein migrates as 65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Background
Syndecan-1 (SYND1 or SDC1) is also known as CD antigen CD138, is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 / SDC1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a useful marker for plasma cells, but only if the cells tested are already known to be derived from blood.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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