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SARS-CoV-2 (COVID-19) S protein RBD (R408I), His Tag

SARS-CoV-2 (COVID-19) S protein RBD (R408I), His Tag

Hersteller	ACROBiosystems
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	SARS-CoV-2
Format	Powder
Menge	100 ug
Host	HEK293
ArtNr	SPD-S52H8-100ug
Konjugat/Tag	Unconjugated, HIS
eClass 6.1	34160400
eClass 9.0	42020190
Lieferbar
Alias	Spike,S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD,COVID-19
Purity	95%
Manufacturers Category	Protein / Viral Proteins
Description	SARS-CoV-2 S protein RBD (R408I), His Tag (SPD-S52H8) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Phe 541 (Accession # QHD43416.1 (R408I)).
Molecule	Spike RBD
Exp Region	Arg 319 - Phe 541
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	27.0 kDa
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.0 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Background	It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

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