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SARS-CoV-2 (COVID-19) S1 protein CTD, His Tag (MALS verified)

SARS-CoV-2 (COVID-19) S1 protein CTD, His Tag (MALS verified)

ArtNr	S1D-C52H3-1mg
Hersteller	ACROBiosystems
Menge	1 mg
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Powder
Specific against	SARS-CoV-2
Host	HEK293
Konjugat/Tag	Unconjugated, HIS
Purity	95%
Citations	(1) Wan Y, et al. J Virol. 2020. pii: JVI.00127-20.<br/>(2) Benvenuto D, et al. J Med Virol. 2020.<br/>(3) Chang CY, et al. AMB Express. 2020. 10(1):20.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	S1 protein CTD,Spike protein S1 CTD,BetaCoV S1-CTD,COVID-19
Lieferbar
Manufacturers Category	Protein / Viral Proteins
Description	SARS-CoV-2 S1 protein CTD, His Tag (S1D-C52H3) is expressed from human 293 cells (HEK293). It contains AA Asn 334 - Pro 527 (Accession # QHD43416.1).
Molecule	Spike CTD
Exp Region	Asn 334 - Pro 527
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	23.6 kDa
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.6 kDa. The protein migrates as 28-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.3
Background	It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

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