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Human S100A14 Protein, His Tag

Human S100A14 Protein, His Tag

ArtNr	S14-H5121-1mg
Hersteller	ACROBiosystems
Menge	1 mg
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Powder
Specific against	Human
Host	E.coli
Konjugat/Tag	Unconjugated, HIS
Purity	95%
Citations	(1) Jin Q., et al., 2011, PLoS ONE 6:E19375-E19375. (2) Chen H., et al., 2012, J. Biol. Chem. 287:17109-17119. (3) Sapkota D., et al., 2012, Oral Oncol. 48:219-225.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	S100A14,S114,S100A15
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Manufacturers Category	Protein / Other Recombinant Proteins
Description	Human S100A14, His Tag (S14-H5121) is expressed from E. coli cells. It contains AA Met 1 - His 104 (Accession # Q9HCY8-1).
Molecule	S100A14
Exp Region	Met 1 - His 104
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	12.5 kDa
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 12.5 kDa. The protein migrates as 13 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin	1.0 EU per μg
Buffer	50 mM Tris, 150 mM NaCl, pH8.0
Background	Protein S100-A14 (S100A14) is also known as S100 calcium-binding protein A14 (S114), which belongs to the S-100 family, containing one EF-hand domain.S100A14 is a homodimer can interact with AGER. S100A14 can modulate P53/TP53 protein levels, and play a role in the regulation of cell survival and apoptosis at different concentrations via receptor for advanced glycation end products (RAGE).S100A14 also plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53.

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Menge: 1 mg

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Lieferung vsl. bis 23.08.2024

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