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Recombinant Human PD-L1 Protein

Recombinant Human PD-L1 Protein

ArtNr	RP02017-100ug
Hersteller	Abclonal
Menge	100 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	Human
Host	Human
Purity	> 95% by SDS-PAGE.
NCBI	B7-H1/PD-L1/CD274
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
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Description	Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Background	B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1 (PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance.
Route	C-His
Manufacturers Category	Proteins
Endotoxin	< 0.1 EU/μg of the protein by LAL method.
Immunogen	Phe19-Arg238
Storage	Store the lyophilized protein at -20°C to -80 °C for long term. After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Manufacturers Research Area	Immune Checkpoint, Bio-Markers & CD Antigens, Biosimilar Drug Targets
Gene Symbol	B7-H1/PD-L1/CD274
Protein Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Protein Description	Recombinant Human 4-1BB/CD137 Protein is produced by mammalian expression system. The target protein is expressed with sequence (Phe19-Arg238) of human PD-L1 (Accession #Q9NZQ7) fused with a 6xHis tag at the C-terminus.
Protein Bio Activity	Immobilized Human PD-L1 at 0.5 μg/mL (100 μL/well), dose response curve for Anti PD-L1 Ab with the EC₅₀ of 8.2 ng/mL determined by ELISA.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug

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Lieferung vsl. bis 27.09.2024

Express-Lieferung: 31 Tage sparen

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