Recombinant Mouse SLAMF2/CD48 Protein

This protein is a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Proteins

Phe23-Arg216

Immune Checkpoint

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Measured by its binding ability in a functional ELISA. Immobilized Human CD48 (Catalog: RP01591) at 10 μg/mL (100 μL/well) can bind Human CD224 (Catalog: RP00167) with a linear range of 0.87-18.4 ng/mL.