Vergleich

Recombinant Human R-spondin-1/RSPO1 Protein Europäischer Partner

ArtNr RP00602-10ug
Hersteller Abclonal
Menge 10 ug
Kategorie
Typ Proteins Recombinant
Specific against Human
Purity > 95% by SDS-PAGE.
Sequence RISAEGSQACAKGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYLHKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVLHAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSRRRKGQQQQQQQGTVGPLTSAGPA
NCBI R-spondin-1/RSPO1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias RSPO1,CRISTIN3,RSPO
Lieferbar
Description
Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.
Background
RSPO1 is a secreted protein, containing 2 FU(furin-like) repeats and 1 TSP type-1 domain and belonging to theR-spondin family. RSPO1 is required for the early development of gonads, regardless of sex. It has been foundin mice only eleven days after fertilization. To induce cell proliferation, it acts synergistically with WNT4. Theyhelp stabilize β catenin, which activates downstream targets. RSPO1 is necessary in female sex development. Itaugments the WNT/ β catenin pathway to oppose male sex development. In critical gonadal stages, betweensix and nine weeks after fertilization, the ovaries upregulate it while the testes downregulate it. RSPO1 canpotentially aid in the treatment of mucositis, which is characterized by inflammation of the oral cavity. Thisunfortunate condition often accompanies chemotherapy and radiation in cancer patients with head and necktumors.
Route
C-6×His
Manufacturers Category
Proteins
Endotoxin
< 1 EU/μg of the protein by LAL method.
Immunogen
Arg31-Ala263
Storage
Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Manufacturers Research Area
Cytokines & Cytokine Receptors
Gene Symbol
R-spondin-1/RSPO1
Protein Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
Protein Description
Recombinant Human R-spondin-1/RSPO1 Protein is produced by Human cells expression system. The target protein is expressed with sequence (Arg31-Ala263) of human R-spondin-1/RSPO1 (Accession #Q2MKA7) fused with a 6×His tag at the C-terminus.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen