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Cynomolgus / Rhesus macaque PTK7 / CCK4 Protein, His Tag (MALS verified)

Cynomolgus / Rhesus macaque PTK7 / CCK4 Protein, His Tag (MALS verified)

ArtNr	PT7-C52H3-1mg
Hersteller	ACROBiosystems
Menge	1 mg
Quantity options	100 ug 1 mg
Kategorie	Peptides & Proteins Enzymes
Typ	Enzymes
Format	Powder
Specific against	Monkey (Cynomolgus, Simian), Rhesus macaque
Host	HEK293
Konjugat/Tag	Unconjugated, HIS
Purity	95%
ECLASS 10.1	32160410
ECLASS 11.0	32160410
UNSPSC	12352204
Alias	PTK7,CCK4,CCK-4,Tyrosine-protein kinase-like 7,Protein-tyrosine kinase 7,Protein-tyrosine kinase 7
Versandbedingung	Raumtemperatur
Lieferbar
Specificity	Cynomolgus / Rhesus macaque
Manufacturer - Category	Protein / Enzymes
Manufacturer - Conjugate / Tag	Unconjugated, C-10xHis
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	76.5 kDa
Description	Cynomolgus / Rhesus macaque PTK7, His Tag (PT7-C52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 39 - Thr 712 (Accession # A0A2K5VNI5-1). In the region Ala 39 - Thr 712, the AA sequence of Cynomolgus and Rhesus macaque PTK7 are homologus.
Background	PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
Molecule	PTK7
Exp Region	Ala 39 - Thr 712
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 76.5 kDa. The protein migrates as 100-110 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution.For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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Arbeitsanleitung (Data Sheet) anfordern

PT7-C52H3-1mg-datasheet.pdf

PT7-C52H3-1mg-safety-datasheet.pdf