Holo Transferrin Bovine ( HTF Bovine )

Bovine Holo Transferrin is a glycoprotein of approximately 80 kDa.

Greater than 97.0% as determined by Cellulose Acetate.

Transferrin is the iron-transport protein of vertebrate serum and donates iron to cells through interaction with a specific membrane receptor, CD71. Transferrin appears to be indispensable for most cells growing in tissue culture. It is referred to frequently as a growth factor because, in analogy to other growth factor-receptor interactions, proliferating cells express high numbers of transferrin receptors, and the binding of transferrin to their receptors is needed for cells to initiate and maintain their DNA synthesis. Apart from its role as an iron transport protein transferrin acts as a cytokine and has functions that may not be related to its iron-carrying capacity.

It is recommended to reconstitute the lyophilized Bovine HTF in sterile 18M-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.