ArtNr |
PRS-XW-RP3028-0.1mg |
Hersteller |
ProSci
|
Menge |
0.1 mg |
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Liquid |
Applikationen |
WB, ELISA, MS |
Specific against |
other |
Dry ice |
Yes
|
ECLASS 5.1 |
34160400 |
ECLASS 6.1 |
34160400 |
ECLASS 8.0 |
42020190 |
ECLASS 9.0 |
42020190 |
ECLASS 10.0.1 |
32160409 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
RO, CRT, SSA, cC1qR, HEL-S-99n, CRTC, Calreticulin, CRP55, ERp60 |
Lieferbar |
|
Applications |
This recombinant protein can be used for WB, ELISA, MS. |
Applications |
This recombinant protein can be used for WB, ELISA, MS. |
Buffer |
10 mM Tris, pH 8.0, 0.002% NaN3, 3mM NaCl, 2.5mM |
Storage Conditions |
Store in working aliquots at -70˚ C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. |
Disclaimer |
For research use only. |
Predicted Molecular Weight |
46 kDa (Calculated) |
Purity |
~90% |
Background |
Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium. |
1St Image Caption3 |
SDS PAGE: Analysis of CALR Recombinant Protein. 4-20% SDS gradient gel. Coomassie blue staining. |
Background References 1 |
Horibe, T., Matsui, H., Tanaka, M., Nagai, H., Yamaguchi, Y., Kato, K. and Kikuchi, M. Gentamicin binds to the lectin site of calreticulin and inhibits its chaperone activity Biochem. Biophys. Res. Commun. 323 (1), 281-287 (2004) |
Accession # |
NP_004334 |
Ncbi Gene Id # |
811 |
Ncbi Official Symbol |
CALR |
Ncbi Official Full Name |
calreticulin |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P27797 |
Sequence |
aa. 18-417 |
Biological Activity |
N/A |
Protein Gi# |
4757900 |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.